Download e-book for iPad: Neurotoxins by P. Michael Conn (Eds.)

By P. Michael Conn (Eds.)

ISBN-10: 0121852652

ISBN-13: 9780121852658

ISBN-10: 0121852660

ISBN-13: 9780121852665

The beautiful simplicity and efficiency of poisons have made them priceless probes of neural structures. This e-book offers a accomplished compilation of thoughts used for the practise, dealing with, and, fairly, for using neurotoxins. version structures are defined within which those neurotoxins were super precious in constructing an realizing of the mobile and molecular foundation of secretion and electrophysiological occasions resulting in altered phone functionality.

Key Features
* handy benchtop format
* equipment awarded for simple edition to new systems
* A digital ''A-B-C'' of ordinary and on hand toxins
* complete protocols integrated for using alpha toxin, apamin, batrachotoxin; botulina toxin, bungarotoxin; channel ligands: agonists and antagonists; capsaicin; charybdotoxin, ciguatoxin; Clostridium botulinum neurotoxin; cholera toxin (choleragen); conotoxin; dendrotoxin; endothelin; fasciculin; geographutoxin; latrotoxin; typical pollution; neosurgatoxin; palytoxin; pertussis toxin; resiniferatoxin; sarafotoxin; scorpion toxin; snake venom toxins

Show description

Read Online or Download Neurotoxins PDF

Best surgery books

Read e-book online Abdominoplastik: Prinzip und Technik (German Edition) PDF

Der renommierte Facharzt für plastische und ästhetische Chirurgie stellt das Gebiet der Abdominoplastik umfassend dar: Angefangen von der historischen Entwicklung bis hin zu den neuesten Verfahren. Eigens angefertigte farbige Zeichnungen vermitteln Konzeption und Planung der verschiedenen Verfahren zur Abdominoplastik und stellen das operative Vorgehen Schritt für Schritt dar.

Download PDF by P. P. Schmittenbecher (auth.), Professor Dr.med. H.-P.: Laser Surgery in Children

This quantity covers present elements of the indicators for using lasers in pediatric surgical procedure. It focusses on prognosis, treatment and result of laser therapy of all appropriate pathological stipulations.

Download e-book for iPad: Medical Management of Kidney Transplantation by Matthew R. Weir MD

This quantity bargains authoritative, evidence-based directions at the complete variety of dilemmas within the scientific administration of kidney transplant recipients ahead of, in the course of, and after transplantation. assurance starts with collection of sufferers who're applicants for transplantation, care of the sufferer at the ready record, and review of donors.

Lasers in aesthetic surgery by Gregory, S. Keller, Victor G. Lacombe, Patrick Lee, James PDF

This accomplished reference covers all features of using lasers in facial cosmetic surgery, from easy technological know-how to surgical thoughts. Introductory chapters supply entire assurance of alternative laser platforms, laser protection, and laser physics. nearly all of the ebook is dedicated to proposing using lasers in dermis resurfacing, therapy of vascular lesions, hair removing, therapy of pigmented lesions and tattoos, and aesthetic surgical procedure.

Additional info for Neurotoxins

Example text

Couraud, J. Biol. Chem. 259, 1491 (1984). a b c d e / h j flat-bottomed 1 [2] APAMIN 21 rated to d r y n e s s u n d e r a gentle stream of nitrogen at 4°C. 6), (2) 2 mCi N a I ( A m e r s h a m ) , and (3) an aliquot of 10 m M Tris-HCl buffer to bring the final reaction volume to 160 /zl. T h e Iodogen tube is incubated at r o o m t e m p e r a t u r e for 20 min, shaking intermittently, and then the c o n t e n t s d e c a n t e d into a clean plastic vial for 10 min. 0 and eluted with the same buffer (1ml fractions, ~ 8 ml/hr).

Neurosci. 10, 237 (1987). 15. G. B. Brown, S. C. Tieszen, J. W. Daly, J. E. Warnick, and E. X. Albuquerque, Cell. Mol. Neurobiol. 1, 19 (1981). 16. G. B. Brown, J. Neurosci. 6, 2064 (1986). 17. M. Cohen-Armon, H. Garty, and M. Sokolovsky, Biochemistry 27, 368 (1988). 18. M. Cohen-Armon and M. Sokolovsky, J. Biol. Chem. 261, 12498 (1986). 19. D. M. Soderlund, R. E. Grubs, and P. M. Adams, Comp. Biochem. Physiol. C 94C, 255 (1989). 20. E. T. McNeal and J. W. Daly, Neurochem. Int. 9, 487 (1986). 21.

T h e constituent h e a v y chain (HC) and light chain (LC) of B o N T s , of M ~ 100,000 and - 5 0 , 0 0 0 , respectively (Fig. 1), are held together by disulfide and noncovalent b o n d s . , B o N T type A ) ; the dichain form of the n e u r o t o x i n s has a higher toxicity than the single-chain form. Despite the lack of antigenic cross-reactivity a m o n g the serologically distinct B o N T s the c o m p a r i s o n of their amino acid composition indicates that they h a v e similar molecular sizes and share a c o m m o n subunit structure ( 1 - 4 ) .

Download PDF sample

Neurotoxins by P. Michael Conn (Eds.)


by Anthony
4.1

Rated 5.00 of 5 – based on 22 votes