Molecular Basis of Membrane-Associated Diseases - download pdf or read online

By E. Van Obberghen, R. Ballotti, Y. Le Marchand-Brustel, J. C. Scimeca (auth.), Prof. Dr. Angelo Azzi, Prof. Zdenek Drahota, Prof. Sergio Papa (eds.)

ISBN-10: 364274415X

ISBN-13: 9783642744150

ISBN-10: 3642744176

ISBN-13: 9783642744174

Biological membranes are usually effected by means of ailments. Molecular occasions resulting in or coming up from pathological adjustments during varied illnesses are as but now not truly understood. This efficient learn by way of major specialists covers adjustments of the mobile atmosphere, membranes and the metabolic features in the course of tissue development and differentiation in addition to elements of irregular organelle functionality in lysosomal garage illnesses, peroxisomal and mitochondrial problems, enzyme defects and regulatory defects of receptors because of oncogenes.

Show description

Read or Download Molecular Basis of Membrane-Associated Diseases PDF

Similar diseases books

Download PDF by Edward F. Plow PHD, Peter Kelly MD (auth.), Arman T. Askari,: Antithrombotic Drug Therapy in Cardiovascular Disease

Sizeable morbidity and mortality continues to be linked to thrombotic occasions has prompted the speedy enlargement of the to be had armamentarium to strive against pathologic thrombosis. Pathologic thrombosis performs an important position within the pathogenesis of acute coronary syndromes (ACS), ischemic problems of percutaneous coronary intervention (PCI), venous thromboembolic illness, and embolic problems of arrhythmias and numerous cardiomyopathies.

Endothelial Dysfunctions and Vascular Disease by Raffaele De Caterina, Peter Libby PDF

Bridging the space among the laboratory and the bedside, this well timed quantity illuminates the relationship among endothelial disorder and vascular sickness. This finished survey of atherosclerotic sickness starts with biology – incorporating the most recent breakthroughs within the box – then elucidates chance elements and diagnostic instruments and markers.

Brucellosis - A Medical Dictionary, Bibliography, and - download pdf or read online

This can be a 3-in-1 reference publication. It offers an entire clinical dictionary masking hundreds of thousands of phrases and expressions in terms of brucellosis. It additionally offers huge lists of bibliographic citations. ultimately, it presents details to clients on easy methods to replace their wisdom utilizing a number of web assets.

Download e-book for kindle: Baseline Evaluation: CINDI Countrywide Integrated by Dipl.-Math. Wolfgang Morgenstern, Dr. Mark S. Tsechkovski

CINDI is an eu intervention programme opposed to significant noncommunicable ailments (NCD). 12 eu nations, Canada, and Israel are engaging within the programme that's coordinated through the realm future health association. The booklet discribes the baseline state of affairs within the nations ahead of the beginning of the programme.

Extra resources for Molecular Basis of Membrane-Associated Diseases

Example text

1986). The association of the Ph' chromosome with ALL is not as frequent as with CML, since only 15% of the cases of ALL are ph +. Within these cases some carry the typical bcr-abl rearrangement and'express P2IO, but a subset does not show any bcr rearrangement. In these patients the chromosome 22 breakpoint appears to be located further upstream, to the left of the breakpoint cluster region (Erikson et al. 1986). It has been recently shown that leukemic cells from these patients express a new altered c-abl protein (P190), oflower molecular weight than P2IO, which still displays enhanced in vitro tyrosine kinase activity, but with different specificity (Clark et al.

J Neurosci 6:2543-2550 Goedert M, Fine A, Hunt SP, Ullrich A (1986) Nerve growth factor mRNA in peripheral and central rat tissues and in the human central nervous system: lesion effects in the rat brain and levels in Alzheimer's disease. Mol Brain Res 1:85-92 Green SH, Rydel RE, Connolly JL, Greene LA (1986) PCI2 mutants that possess low- but not high-affinity nerve growth factor receptors neither respond to nor internalize nerve growth factor. J Cell Bioi 102:830-843 Greenberg ME, Greene LA, Ziff EB (1985) Nerve growth factor and epidermal growth factor induce rapid transient changes in proto-oncogene transcription in PCI2 cells.

1985, 1987; Pierce et al. 1985; Mathey-Prevot et al. 1986; Rovera et al. 1987). The associa tion ofP21 0, a constitutively active tyrosine kinase, with CML cells, strongly suggests that such an enzymatic activity may be involved in their uncontrolled proliferation, perhaps releasing them from their dependence on specific limiting growth factors. Recent gene transfer experiments involving expression of the bcr-abl protein in NIH/3T3 fibroblasts, show that P2IO differs from Pl60 v-abl, since it is not capable of causing fibroblast transformation (Daley et al.

Download PDF sample

Molecular Basis of Membrane-Associated Diseases by E. Van Obberghen, R. Ballotti, Y. Le Marchand-Brustel, J. C. Scimeca (auth.), Prof. Dr. Angelo Azzi, Prof. Zdenek Drahota, Prof. Sergio Papa (eds.)


by William
4.2

Rated 4.91 of 5 – based on 16 votes