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Of 182 study patients, 38 (21%) were considered to have healthcare-onset infections. The age distribution of 1218 300 S. aureus MRSA No. infections 250 200 150 100 50 0 3 4 1 2 2002 3 4 1 2003 2 2004 Quarter and year Figure 1. Number of Staphylococcus aureus and methicillinresistant S. aureus (MRSA) infections by quarter and year, center A, August 2002–July 2004. N = 1,553. the healthcare-onset and community-onset groups differed with median ages of 59 and 7 years, respectively (Figure 3). Twenty percent of the community-onset group was <2 years of age compared with 3% in the healthcare-onset group.

20) described nosocomial transmission in an outbreak setting among postpartum women in New York City and in San Francisco. Carleton et al. (31) found a proportion of nosocomial MRSA isolates with molecular typing consistent with community strains. 5-month prospective study in 2004, Seybold et al. (21) found that 20% of nosocomial MRSA bloodstream infections were due to USA300, a CA-MRSA strain type. In our study, 38 (21%) hospitalized patients with CA-MRSA strain type infections met our definition for having healthcare-onset infections.

2003;41:5113–20. 2003 28. Diep BA, Carleton HA, Chang RF, Sensabaugh GF, PerdreauRemington F. Roles of 34 virulence genes in the evolution of hospital- and community-associated strains of methicillin-resistant Staphylococcus aureus. J Infect Dis. 2006;193:1495–503. 1086/503777 29. Donnio PY, Preney L, Gautier-Lerestif AL, Avril JL, Lafforgue N. Changes in staphylococcal cassette chromosome type and antibiotic resistance profile in methicillin-resistant Staphylococcus aureus isolates from a French hospital over an 11 year period.

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Emerging Infectious Diseases - Vol. 14, No.8, August 2008 by Centers for Disease Control and Prevention

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