Download e-book for iPad: Electrophysiologic Testing in Disorders of the Retina, Optic by Gerald Allen Fishman M.D., David G. Birch Ph.D., Graham E.

By Gerald Allen Fishman M.D., David G. Birch Ph.D., Graham E. Holder Ph.D., Mitchell G. Brigell Ph.D.

ISBN-10: 1560551984

ISBN-13: 9781560551980

This moment version is considerably improved, with broader and deeper assurance. contains new chapters at the focal and multifocal electroretinogram and the development ERG. additionally covers visible evoked capability, development dystrophies, North Carolina macular dystrophy, innovative bifocal macular dystrophy, sheen retinal dystrophies, neuronal ceroid lipofuscionoses, retinal degeneration with spinocerebellar ataxia, greater S-cone syndrome, and extra.

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Extra resources for Electrophysiologic Testing in Disorders of the Retina, Optic Nerve, and Visual Pathway (Ophthalmology Monographs)

Example text

The photopic and scotopic implicit times, unlike those found with the Schubert-Bornschein pattern, are more similar to the normal time relationships anticipated under photopic and scotopic conditions. Patients with CSNB appear to have a normal amount or density of rod visual pigment in situ and, in the Schubert-Bornschein type, a normal a-wave. Further, the rod photopigment-regeneration kinetics are entirely normal. In such cases, the photoreceptor cells are therefore intact and the primary defect does not reside within the outer segments of these cells, but rather in the transmission of their visually evoked signal.

Such patients have a nonprogressive visual disorder and therefore would best be described as having a cone dysfunction rather than a dystrophy, which implies a progressive deterioration of function. The term monochromat reflects these patients' perception of all colors as shades of gray. The rod photoaversion, nystagmus, decreased visual acuity, and poor color perception. Generally, they have a normal fundus or only minimal, nonspecific pigment changes within the macula. 200,201 The incomplete rod monochromat is similar in characteristics to the complete form, except for less extensive involvement.

In the incomplete type, the OPs are more frequently recordable than in the complete type. 228 Many patients in the complete group have high or moderate myopic refractive errors, while those in the incomplete group tend to have mild myopic 1-10 Stationary or hyperopic refractive errors. 229 To date, no pedigree has convincingly shown a complete and an incomplete type in the same family. ERG recordings, in addition to psychophysical measurements, are of obvious value in distinguishing these two distinct subtypes.

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Electrophysiologic Testing in Disorders of the Retina, Optic Nerve, and Visual Pathway (Ophthalmology Monographs) by Gerald Allen Fishman M.D., David G. Birch Ph.D., Graham E. Holder Ph.D., Mitchell G. Brigell Ph.D.


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