By M.J. Elder, W. Bernauer, J.K.G. Dart, F. Bandello
Cicatrizing conjunctivitis is among the such a lot hard motives of ocular floor affliction at the present time, and with no applicable intervention, corneal blindness or lack of sight from supervening an infection is usual. simply because a lot of those ailments are infrequent, there's frequently constrained administration event to be had and the assets for study into remedy and pathogenesis could be scarce. this article summarizes current remedy thoughts and the medical and laboratory experiences validating those methods. subject matters mentioned contain an in-depth examine non-progressive factors together with trachoma, Stevens-Johnson syndrome and ligneous conjunctivitis. The textual content additionally examines persistent revolutionary conjunctival cicatrization, the ailments which reason it, their medical and laboratory evaluate, immunopathogenesis, sequelae and administration. it's going to relief the making plans of intervention and remedy of a gaggle of ailments formerly linked to bad analysis.
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Extra resources for Cicatrising Conjunctivitis (Developments in Ophthalmology)
Corneal scarring and vascularisation may occur as a result of corneal involvement in the acute phase of the disease, or as a result of the various processes described above. These corneal changes and the abnormal tear film can combine to affect vision. Impaired vision and chronic discomfort are common in patients who have had Stevens–Johnson syndrome [19, 20]. The typical chronic phase of the disease is seen in figure 3. Management Diagnosis In both the acute and the chronic phase, the diagnosis of Stevens–Johnson syndrome is based on clinical findings.
These surfaces become inflamed, blister and ulcerate [12, 13]. In addition, the patient tends to be unwell with fever, joint and muscle aches, perhaps a sore throat, or even nausea and vomiting. During the acute phase, even apparently unaffected areas of the skin may be inclined to blister when rubbed. This has been termed the ‘Nikolsky sign’. Clinical Features – Ocular In the acute phase of the disease, patients develop a non-specific conjunctivitis which may progress to bulla formation and ulceration.
Invest Ophthalmol Vis Sci 1992;33:268–272. Rapoza PA: Epidemiology of neonatal conjunctivitis. Ophthalmology 1986;93:456–461. Armstrong JH, Zacarias F, Rein MF: Ophthalmia neonatorum: A chart review. Pediatrics 1976; 57:884–892. Sheppard JD, Kowalski RP, Meyer MP, Amortgui AJ, Slifkin M: Immunodiagnosis of adult chlamydial conjunctivitis. Ophthalmology 1988;95:434–443. Heggie AD, Jaffe AC, Stuart LA: Topical sulfacetamide versus oral erythromycin for neonatal chlamydial conjunctivitis. Am J Dis Child 1985;139:564–566.
Cicatrising Conjunctivitis (Developments in Ophthalmology) by M.J. Elder, W. Bernauer, J.K.G. Dart, F. Bandello