By Richard A Prayson; Mark L Cohen; Bette Kleinschmidt-DeMasters
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Additional resources for Brain tumors
For primary malignant gliomas, focal or regional symptoms evolving over days to a few weeks are typical. However, low-grade primary brain tumors most commonly cause the new onset of seizures and it is this ictal event that leads to a diagnosis. Benign extra-axial tumors (meningiomas and schwannomas) can cause more subtle ﬁndings that may be present for years prior to diagnosis. Although these generalizations are helpful, it must be remembered that the clinical presentation of patients with central nervous system tumors can be variable.
Neurooncology has evolved into a multidisciplinary collaborative specialty that combines the expertise from radiation oncologists, neuroradiologists, neurologists, pathologists, and medical oncology. Each of these specialties provides important components of comprehensive care. Current management strategies can optimize outcomes by integrating not only the standard of care, but also novel and investigative therapies. The challenge of surgical neurooncology is to reduce the tumor burden, minimize symptoms, preserve functional abilities, and manage the initial stages of treatment.
This is true no matter how irradiation is delivered. It is important to be cognizant of what is safe and what is of uncertain safety as different radiotherapy fractionation schemes are prescribed and delivered to varying volumes that include different amounts and types of normal tissues. Principles of Radiation Therapy 19 Radiation management of neurooncologic problems also involves a critical assessment of the appropriateness of the use of radiation therapy in one or another fashion for each individual patient.
Brain tumors by Richard A Prayson; Mark L Cohen; Bette Kleinschmidt-DeMasters