By L. Bulow
In December 1992, the dep. of natural and utilized Biochemistry on the Chemical heart in Lund, Sweden, equipped a global assembly, the Mosbach Symposium on Biochemical know-how, to rejoice the sixtieth birthday of professor Klaus Mosbach, one of many founders of recent biotechnology. The historical past of natural and utilized Biochemistry had its begin in 1970, a number of years after the basis of the Chemical heart. Klaus Mosbach has been its professor and head of natural and utilized Biochemistry for the reason that its begin. throughout the 1980's he additionally maintained a professorship on the ETH in Z?rich, Switzerland. Professor Mosbach is the world over recognized and he has world-leading place in the box of immobilization of bioactive components and cells in addition to affinity chromatography. In 1990, Professor Mosbach was once provided the gold medal through the Royal Swedish Academy of Engineering Sciences for his contributions to biotechnology, specially at the immobilization of bioactive components. The learn actions of the dept of natural and utilized Biochemistry disguise a huge zone, similar to affinity and separation ideas, bioprocess regulate, biosensors, improvement of recent providers and new immobilization systems for small molecules in addition to proteins and cells, together with animal and plant cells, gene expertise, approaches according to immobilized biocatalysts, and development of natural polymers with enzyme-like houses. The hallmark of the dep. is its different study that generates enormous synergistic results which are manifested by way of many new recommendations and ideas emanating from the laboratory over the past two decades. a number of of those are advertised via a number of biotechnology businesses. At this assembly we consequently prepared for a few of the world's prime specialists in biochemistry and biotechnology to provide lectures. the subjects coated include enzyme know-how, immobilization of enzymes and cells, abzymes, metabolic engineering, biosensors, and molecular popularity. The legit reward from the symposium committee and the individuals is that this "Festschrift" which covers numerous very important fields of study in the region of biochemical know-how. now we have made a truly strange method and feature allow the "hero of the social gathering" current the historical past of his examine.
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Extra resources for BIochemical Technology
I. INTRODUCTION.. . . . . . . . . . . . . . . . 11. NEW AREAS OF BIOSENSORS . . . . . . . . . . . . 111. STATUS OF BIOSENSOR SALES AND RESEARCH . . . . . . 365 366 366 . 370 ABSTRACT Biosensors, first described in the early 1960s,have advanced in 30 years to an age of sophistication. Electrochemical biosensors, the first of such sensors, have become with improved methods of electron transfer, better immobilization procedures, and miniaturization a 500 million dollar business.
From this objective search (conducted in the period January, 1987 to February, 1992 by Professor R. Schmid of the GBF in Braunschweig) (Mascini, 1992), we can see how the United States and Japan are important as single nations, but, also, how the EEC is highly productive as a whole (1244 entries vs. 1284 in Japan and 864 in the United States). In a comparison of patent productivity in the EEC, Japan, and the United States, only 183 patents in this period were obtained by the whole of Europe vs.
Coulometric generation of the cosubstrate oxygen is the basis of the ovgen-stabilized glucose electrode. The oxygen consumed in the enzyme reaction is regenerated by water electrolysis at an auxiliary electrode. The consumed charge reflects the amount of the converted substrate and this principle allows measurement even in solutions of changing oxygen content (Cleland and Enfors, 1984). V. ORGANIC PHASE BIOSENSORS The potential advantages of using enzymes in organic as opposed to aqueous solutions include increased solubility of many organic substrates, reversion of hydrolytic reactions, relative ease of enzyme immobilization based on their insolubility in organic solvents, elimination of microbial contamination,and reduction of side reactions.
BIochemical Technology by L. Bulow