By Ronald R. Watson
The 1st connection with gather the most recent study and experiences at the remedy and pathogenesis of middle sickness in AIDS sufferers, this reference makes an attempt to enhance the analysis, administration, and treatment of HIV-associated middle failure by means of learning the lengthy results of immunosuppression and opportunistic and viral an infection, in addition to cofactors affecting middle affliction reminiscent of drug-related cardiotoxicity, cocaine abuse, and dietary deficiencies on cardiac functionality.
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Surgery 1997; 121:513–519. 32. Gariano RF, Rickman LS, Freeman WR. Ocular examination and diagnosis in patients with the acquired immunodeficiency syndrome. West J Med 1993; 158(3):254–262. 33. Rhodes RH. Evidence of serum-protein leakage across the blood-brain barrier in the acquired immunodeficiency syndrome. J Neuropathol Exp Neurol 1991; 50(2): 171–183. 34. Joshi VV, Pawel B, Connor E, Sharer L, Oleske JM, Morrison S, Marin-Garcia J. Arteriopathy in children with acquired immune deficiency syndrome.
4a). By flow cytometry, Mechanisms of atherogenesis in HIV infection 19 enhanced expression of VCAM-1 on endothelial cell surfaces was seen with both tat protein and IL-1 β (Fig. 4b). Similar upregulation of cell surface ICAM-1 by IL-1 β was seen. These adhesion molecules are important under normal inflammatory conditions in the adherence of leukocytes to the endothelium, ultimately allowing the immune cells to leave the vasculature and infiltrate the surrounding vascular tissue. Our data as well as the recent observation that tat activates nuclear translocation of NF-κB (70) are significant.
50. Steffan AM, Lafon ME, Gendrault JL, Schweitzer C, Royer C, Jaeck D, Arnaud JP, Schmitt MP, Aubertin AM, Kirn A. Primary cultures of endothelial cells from the human liver sinusoid are permissive for human immunodeficiency virus type 1. Proc Natl Acad Sci USA 1992; 89:1582–1586. 51. Steffan AM, Lafon ME, Gendrault JL, Smedsrod B, Nonnenmacher H, Koehren F, Gut JP, de Monte M, Martin JP, Royer C, Kirn A. Productive infection of primary cultures of endothelial cells from the cat liver sinusoid with the feline immunodeficiency virus.
AIDS and Heart Disease by Ronald R. Watson